Amphotericin 0.5% (5mg/mL) Ophthalmic Solution

Amphotericin sterile ophthalmic solution for topical ophthalmic use. An anti-fungal for treating fungal keratitis.

• Volume: 10ml
• Concentration: 0.5%
• Also available as an ointment
• We exclusively compound Amphotericin sterile ophthalmic solution for ophthalmic use only
• Compounded in a sterile compounding facility that is <795>, <797> and <800> chapter compliant

References:

1. Wood TO, Williford W. Treatment of keratomycosis with amphotericin B 0.15%. Am J Ophthalmol. 1976;81(6):847-849. PMID: 779483. https://pubmed.ncbi.nlm.nih.gov/779483/
2. Mahdy RA, Nada WM, Wageh MM. Topical amphotericin B and subconjunctival fluconazole vs topical amphotericin B in keratomycosis. J Ocul Pharmacol Ther. 2010;26(3):281-285. PMID: 20565316. https://pubmed.ncbi.nlm.nih.gov/20565316/
3. Kaushik S, Ram J, Brar GS, Jain AK, Chakraborti A, Gupta A. Intracameral amphotericin B: initial experience in severe keratomycosis. Cornea. 2001;20(7):715-719. PMID: 11588423. https://pubmed.ncbi.nlm.nih.gov/11588423/
4. Kuriakose T, Kothari M, Paul P, Jacob P, Thomas R. Intracameral amphotericin B injection in the management of deep keratomycosis. Cornea. 2002;21(7):653-656. PMID: 12352080. https://pubmed.ncbi.nlm.nih.gov/12352080/
5. Efficacy and Safety of Intracameral Amphotericin B for Fungal Keratitis: a systematic review. Int J Antimicrob Agents. 2026; in press. (Systematic analysis of intrastromal/intracameral amphotericin B for keratitis). DOI:10.1016/j.ijantimicag.2025.107707 (PubMed indexed upon final publication).https://www.sciencedirect.com/science/article/abs/pii/S0924857925002626?utm_source