Prescribed solutions for men and women experiencing hair loss or thinning requires compounded solutions to address the complex biology of the hair follicle in a way that over-the-counter medications cannot.
The treatment involves more than two dozen variables that need to be addressed with the highest-quality and most potent APIs to achieve successful outcomes.
- Stem cell stimulation
- Opening ion channels within cells
- Suppression of dihydrotestosterone (DHT)
- The exertion of antioxidant effects
- Extension of anagen growth phase
- Expression of vascular endothelial growth factor
- Blockade of chronic inflammation
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- Male patient, age 24, struggled with advanced male pattern hair loss. The prescriber recommended a compounded solution combining minoxidil, biotin, and finasteride over 90 days.
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- Female patient struggled with female pattern hair loss. A compounded solution combining minoxidil and biotin for 90 days was prescribed.
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- Male patient, age 53, struggled with age-related hair loss. The compounded solution used included Minoxidil 10%/Cetirizine 1%/Finasteride 0.1%.
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- Female patient, age 42, with bald spot. The compounded solution used included Minoxidil 10%/Cetirizine 1%/Estradiol 0.025%/Fluocinolone 0.025%.
Custom-Made Compounded Medications for Hair Loss
Our easy-to-use formulas integrate easily into daily routines and address these variables by offering a prescriber the ability to formulate a multi-phasic compound with ingredients such as:
Minoxidil (various strengths for men and women)
An antihypertensive vasodilator medication that can slow and stop hair loss and stimulate new growth. The only FDA-approved ingredient to treat hair loss and thinning. Known commercially as Rogaine. Can be formulated at dosages that are prescription-strength (5% and above).1
Finasteride
Applied topically, finasteride yields results comparable to oral administration but without the sexual side effects.2
Estradiol and progesterone
Endogenous sex hormones that play a key role in hair loss.3
Fluocinolone
A topical steroid used to treat skin conditions such as eczema, which can impact the thickness and fullness of hair.4
Retinoic acid
Topical application of all-trans retinoic acid (tretinoin) has been shown to promote hair growth, especially when combined with minoxidil.5,6
Biotin and saw palmetto
Some small studies have shown that saw palmetto (Serenoa repens) may reduce hair loss.7,8 A combined treatment of biotin and saw palmetto has been clinically shown to decrease hair loss in both men and women.9
Proprietary biopeptide blend
Peptides have various benefits for promoting hair growth and color. GHK-Cu has been shown to increase hair follicle size,10 while Palmitoyl Tetrapeptide-20 has been shown to prevent the premature graying of hair.11
References
| 1. Goren A, Naccarato T. Minoxidil in the treatment of androgenetic alopecia. Dermatol Ther. 2018;31(5). doi:10.1111/DTH.12686 |
| 2. Lee SW, Juhasz M, Mobasher P, Ekelem C, Mesinkovska NA. A Systematic Review of Topical Finasteride in the Treatment of Androgenetic Alopecia in Men and Women. J Drugs Dermatol. 2018;17(4):457. Accessed September 12, 2022. /pmc/articles/PMC6609098/ |
| 3. Grymowicz M, Rudnicka E, Podfigurna A, et al. Hormonal Effects on Hair Follicles. Int J Mol Sci. 2020;21(15):1-13. doi:10.3390/IJMS21155342 |
| 4. Pascher F, Kurtin S, Andrade R. Assay of 0.2 % Fluocinolone Acetonide Cream for Alopecia Areata and Totalis. Dermatology. 1970;141(3):193-202. doi:10.1159/000252466 |
| 5. Oh SK, Hyun KP, Youn JO, et al. Promotive Effect of Minoxidil Combined with All-trans Retinoic Acid (tretinoin) on Human Hair Growth in Vitro. J Korean Med Sci. 2007;22(2):283. doi:10.3346/JKMS.2007.22.2.283 |
| 6. Sharma A, Goren A, Dhurat R, et al. Tretinoin enhances minoxidil response in androgenetic alopecia patients by upregulating follicular sulfotransferase enzymes. Dermatol Ther. 2019;32(3):e12915. doi:10.1111/DTH.12915 |
| 7. Prager N, Bickett K, French N, Marcovici G. A randomized, double-blind, placebo-controlled trial to determine the effectiveness of botanically derived inhibitors of 5-alpha-reductase in the treatment of androgenetic alopecia. J Altern Complement Med. 2002;8(2):143-152. doi:10.1089/ACM.2002.8.143 |
| 8. Rossp A, Marp E, Scarn02 M, et al. COMPARITIVE EFFECTIVENESS OF FINASTERIDE vs SERENOA REPENS IN MALE ANDROGENETIC ALOPECIA: A TWO-YEAR STUDY. Int J Immunopathol Pharmacol. 2012;25(4):1167-1173. |
| 9. Narda M, Aladren S, Cestone E, Nobile V. Efficacy and Safety of a Food Supplement Containing L-cystine, Serenoa repens Extract and Biotin for Hair Loss in Healthy Males and Females. A Prospective, Randomized, Double-blinded, Controlled Clinical Trial. J Cosmetol Trichology. 2017;3(3):1-8. doi:10.4172/2471-9323.1000127 |
| 10. Pickart L. The human tri-peptide GHK and tissue remodeling. https://doi.org/101163/156856208784909435. 2012;19(8):969-988. doi:10.1163/156856208784909435 |
| 11. Scalvino SA, Chapelle A, Hajem N, et al. Efficacy of an agonist of α-MSH, the palmitoyl tetrapeptide-20, in hair pigmentation. Int J Cosmet Sci. 2018;40(5):516-524. doi:10.1111/ICS.12494 |
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