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Compounding For Sclerotherapy – Spider Vein And Varicose Vein Injections

Custom sclerotherapy solutions to replace commercial Sotradecol®
compounding for sclerotherapy

The impending discontinuation of Sotradecol (sodium tetradecyl sulfate solution) by the FDA will reduce the options available to patients suffering from weakened veins with faulty valves that have become abnormally enlarged, painful or cosmetically unsightly.

At VLS Pharmacy and New Drug Loft we compound a variety of doses of sodium tetradecyl sulphate to treat veins in cases where Sotradecol would typically be considered.


Sodium tetradecyl sulfate solution is a sterile anionic surfactant solution that acts as a sclerosing agent to stimulate intimal inflammation and thrombus formation. While not a permanent solution for varicose veins it is effective at diminishing smaller varicose veins and most spider veins.


The benefit of compounding is the ability to create truly custom dosages that meet your patients’ needs. Common commercial doses range from 1% to 3%.


As with Sotradecol, common contraindications for our compounds still apply, including the consideration of potential drug interactions, patients suffering from clotting disorders, blood infections and allergic hypersensitivities. Compression stockings post-treatment are recommended. For full details, speak to our expert pharmacy team.

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